약학대학 전임교수 목록

교수진/연구실
교수진
전임교수

교수정보의 상세 화면
이름 박상규 학력 박사 전공 약학전공(과)
정보	연구실 : 종합관 608호 연구실번호 : 3453 이메일 : sgpark@ajou.ac.kr 연구관심분야 : Stem Cells/Cancer/Drug Development 홈페이지1 : http://www.genefunctionlab.com
학력	졸업연도/학교/학위 2005.02 서울대학교 박사
경력	2007~2009 Assistant professor, Clinical Research Institute, Seoul National University Hospital 2009.09~2014.09 Adjunctive professor, Graduate School of Convergence Science and Technology, Seoul National University 2009~2014.08 Associate professor, Department of Biomedical Science, College of Life Science, CHA University 2014.09~present Associate professor, Dept.of Pharmacy, College of Pharmacy, AJOU University
연구분야	Function Hunting of Med28 Med28 was recently identified as a mediator of transcription complex, which involved in tumorigenesis including breast cancer, prostate cancer. However, its molecular mechanism is not understood. So we isolated binding candidates of med28, and are trying to unveil the molecular mechanism. Many candiates are shown to be associated with cancer progression such as DNA repair, chromosome segregation, suppressor of tumor suppressor, cell-cell signaling. Thus we are studying about the novel regulatory mechanism in cancer onset and progression. p43/AIMP1 and Stem Cell p43/AIMP1 has been known as a multi-functional protein, which take part in immune cell activation, angiogenesis, blood glucose regulation, and wound healing as a cytokine. In addition, p43/AIMP1 regulates TGFb signaling and autoimmune disease in cytoplasm. Interestingly, whole body knock-out of p43/AIMP1 in mouse shows multiple phenotypes including defect of uterus development, petite, ataxia and so on... Thus we generated conditional knock-out mouse to remove p43/AIMP1 tissue specifically. In addition, we are investigating whether the p43/AIMP1 could regulate stem cell mobilization from bone marrow, self-renewal, and differentiation of bone marrow-derived mesenchynal stem cell or hematopoietic stem cell. Furthermore, we are studying if the p43/AIMP1 would clinically applicable. Development of Stem Cell Mobilizer Many clinicians are trying to treat diseases using stem cell. In some case, stem cells should be isolated from peripheral blood and manipulated in vitro to enrich stem cell. Big problem of in vitro manipulation of stem cell is genetic instability. If the stem cell mobilizer would be available, there could be a large amount of stem cell in peripheral blood. if so, we could minimize the genetic instability in vitro. Thus we are screening chemicals to induce stem cell mobilization. Development of Therapeutic Antibody Currently, we are developing therapeutic antibody, targeting rheumatoid arthritis(RA). Recently, we found that AIMP1 cytokine promoted osteoclastogenesis of macrophages and its level is increased in synovial fluid of RA patients. So we generated monoclonal antibody that neutralizes AIMP1 cytokine, and further developed chimeric antibody, which shows efficient attenuation of arthritis in collagen-induced arthritis mouse model. We developed fully humanized antibody, and are performing preclinical study. We are expecting that the atlizumab would be applicable to human body for the treatment of RA.
논문 및 연구활동	연구활동(주요논문) [논문] 박상규, 이준희, 홍신희, 이한나, 김철민, 권상모, 윤강준, 오배준, 김재현, 정석윤, Takayuki Asahara, 조진구, 김서윤, Tauroursodeoxycholic Acid, a Bile Acid, Promotes Blood Vessel Repair by Recruiting Vasculogenic Progenitor Cells , STEM CELLS , pp.1 -10 (Nov, 2014) [논문] 박상규, 이택기, 김왕균, 최준석, 송승용, 한준희, 성종혁, 김원석, 이현주, 조윤경, 황성주, 송순욱, 김지혜, Isolation of adipose-derived stem cells by using a subfractionation culturing method , EXPERT OPINION ON BIOLOGICAL THERAPY , Vol.14 , No.11 , pp.1551 -1560 (Nov, 2014) [논문] 박상규, 성종혁, 송순욱, 김지혜, 김왕균, Functional Regulation of Adipose-derived Stem Cells by PDGF-D , STEM CELLS , pp.1 -8 (Oct, 2014) [논문] 박상규, 조진구, 김철민, 강아영, 박경수, 안병용, 정성수, 임기환, 백광현, 성종혁, 이경원, 김민, Herpesvirus-associated ubiquitin-specific protease (HAUSP) modulates peroxisome proliferator-activated receptor γ (PPARγ) stability through its deubiquitinating activity , JOURNAL OF BIOLOGICAL CHEMISTRY , Vol.288 , No.46 , pp.32886 -32896 (Nov, 2013) [논문] 박상규, 손우성, 이수홍, 김철민, 차병현, 윤강준, 김서윤, 박민철, ARS-interacting multi-functional protein 1 induces proliferation of human bone marrow-derived mesenchymal stem cells by accumulation of β-catenin via fibroblast growth factor receptor 2-mediated activation of Akt , STEM CELLS AND DEVELOPMENT , Vol.22 , No.19 , pp.2630 -2640 (Oct, 2013) 국제학술논문지 [논문] 서원희, 여영주, 이은희, 김정민, 서송이, 김률이, 김경리, 성종혁, 박상규, 조은경, FGF12 (Fibroblast Growth Factor 12) Inhibits Vascular Smooth Muscle Cell Remodeling in Pulmonary Arterial Hypertension , HYPERTENSION , pp.1778 -1786 (Dec, 2020) [논문] 박상규, 김진옥, 김하늘, 허덕림, 백은지, 박정양, 하경수, 서민덕, 김광혁, Development and characterization of a fully human antibody targeting SCF/c-kit signaling , INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES , pp.1 -48 (May, 2020) [논문] 서원희, 김경리, 서송이, 김지택, Yeongju Yeo, 김원, 성종혁, 박상규, 김재택, SCF (Stem Cell Factor) and cKIT Modulate Pathological Ocular Neovascularization , ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (Aug, 2019) [논문] 박상규, 김진옥, 안성수, 윤태준, 이상원, 고은희, 노희동, 박용범, 정학준, 김태성, 문진희, 김수정, Atializumab, a humanized anti-aminoacyl-tRNA synthetases-interacting multifunctional protein-1 (AIMP1) antibody significantly improves nephritis in (NZB/NZW) F1 Mice Biomaterials , BIOMATERIALS (Aug, 2019) [논문] 박상규, 김진옥, 이상원, 송정식, 박용범, 안성수, 윤태준, Serum aminoacyl-tRNA synthetase-interacting multifunctional protein-1 can predict severe antineutrophil cytoplasmic antibody-associated vasculitis: a pilot monocentric study , BIOMED RESEARCH INTERNATIONAL (May, 2019) [논문] 박상규, 최준석, 이재호, 김진옥, 김홍숙, 노희동, 임기환, 박병준, 조진구, 조민국, MED28 over-expression shortens the cell cycle and induces genomic instability , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Apr, 2019) [논문] 박상규, 박경수, 김석호, 홍신희, 김형수, 서원희, 이경원, 정기원, 임창진, 김진희, 박영준, 성종혁, MD001, a Novel Peroxisome Proliferator-activated Receptor α/γ Agonist, Improves Glucose and Lipid Metabolism , SCIENTIFIC REPORTS , pp.1 -12 (Feb, 2019) [논문] 윤태종, 박상규, 류지연, 박혜선, 이한아름, 홍신희, 홍관수, 김홍표, 조은이, Lechitin nano-liposomal particle as a CRISPR/Cas9 complex delivery system for treating type 2 diabetes , Journal of Nanobiotechnology , pp.19 -31 (Jan, 2019) [논문] 박상규, 홍신희, 이상원, 정승민, 제이슨 송 정식, 박용범, 안성수, 박윤희, Serum aminoacyl-tRNA synthetase-interacting multifunctional protein-1 (AIMP1), a novel disease activity predictive biomarker of systemic lupus erythematosus. , CLINICAL AND EXPERIMENTAL RHEUMATOLOGY , Vol.36 , No.4 , pp.533 -539 (Jul, 2018) [논문] 정동근, 권성률, 반원진, 임현아, 김은주, 박헌용, 조용기, 박상규, 서영식, Effects of the generated functional groups by PECVD on adhesiveness of adipose derived mesenchymal stem cells , JOURNAL OF VACUUM SCIENCE & TECHNOLOGY A , Vol.36 , No.3 (May, 2018) [논문] 박상규, 임기환, 조진구, MED28 increases the colony-forming ability of breast cancer cells by stabilizing the ZNF224 protein upon DNA damage , ONCOLOGY LETTERS , Vol.15 , No.3 , pp.3147 -3154 (Mar, 2018) [논문] 박상규, Youn christine, 김정형, 신영기, 안종찬, 홍성렬, 김영덕, 이명석, 박병준, Enhanced cell growth of adipocyte-derived mesenchymal stem cells using chemically-defined serum-free media , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (Aug, 2017) [논문] 박상규, 장수아, 이정호, 손보경, 김어수, 남궁기, 박민선, 김은우, 정지헌, 이정영, 김철훈, 윤강준, Suppression of AIMP1 protects cognition in Alzheimer's disease model mice 3xTg-AD , NEUROREPORT , pp.1 -5 (Nov, 2016) [논문] 박상규, 윤강준, 조영준, 엄윤정, 조진구, 홍신희, 임기환, Tauroursodeoxycholic acid improves viability of artificial RBCs , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , pp.1682 -1687 (Sep, 2016) [논문] 박상규, 송선화, 김경종, 조은경, 서원희, 권진숙, 배선식, 성종혁, 김지택, 김영욱, Fibroblast Growth Factor 12 is a Novel Regulator of Vascular Smooth Muscle Cell Plasticity and Fate , ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY , pp.1928 -1936 (Sep, 2016) [논문] 박상규, 김지혜, 윤세미, 박인국, 김원석, 이진우, 성종혁, 송순욱, Hypoxia Suppresses Spontaneous Mineralization and Osteogenic Differentiation of Mesenchymal Stem Cells via IGFBP3 Up-Regulation , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , pp.1 -15 (Aug, 2016) [논문] 박상규, 박세호, 임채현, 김홍숙, 임기환, 노태영, 성종혁, 서원희, 함석진, 조진구, 송승용, ZNF224, Kruppel like zinc finger protein, induces cell growth and apoptosis-resistance by down-regulation of p21 and p53 via miR-663a , ONCOTARGET , pp.31177 -31190 (May, 2016) [논문] 박상규, 조혜은, 심영기, 강태진, 김지천, 최준석, Identification of diagnostic biomarkers for early detection of anthrax from human aortic endothelial cells , INTERNATIONAL JOURNAL OF NANOTECHNOLOGY , pp.413 -425 (May, 2016) [논문] 박상규, 김소라, 임지은, 정지훈, 서원희, 김지택, 우세준, 성종혁, 김지연, The cKit Inhibitor, Masitinib, Prevents Diabetes-Induced Retinal Vascular Leakage , INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE , pp.1201 -1206 (Mar, 2016) [논문] 박상규, Hemant Kumar, 이수홍, 박세아, Yopshie Arai, 한인보, 안종찬, 차병현, AIMP1 downregulation restores chondrogenic characteristics of dedifferentiated/degenerated chondrocytes by enhancing TGF-β signal , CELL DEATH & DISEASE -12 (Feb, 2016) [논문] 박상규, 손미권, 홍순선, 김광일, 김기진, 이수홍, 안종찬, 정경희, Aminoacyl-tRNA synthetase interacting multi-functional protein 1 attenuates liver fibrosis by inhibiting TGFβ signaling , INTERNATIONAL JOURNAL OF ONCOLOGY , Vol.48 , No.2 , pp.747 -755 (Feb, 2016) [논문] 박상규, Anuchit Plubrukarn, Jong?Hyuk Sung, Seok?Ho Kim, Jin?Hyun Jeong, 조진구, Sireewan Kaewsuwan, Maleeruk Utsintong, Interruptin B induces brown adipocyte differentiation and glucose consumption in adipose-derived stem cells , MOLECULAR MEDICINE REPORTS , pp.1 -9 (Jan, 2016) [논문] 박상규, 임기환, Transcriptional regulation of KRAB-ZFPs in cancer , MOLECULAR & CELLULAR TOXICOLOGY , Vol.11 , pp.389 -394 (Dec, 2015) [논문] 최진우, 최준석, 김준기, 양윤정, 김필한, 조은영, 이대호, 박상규, 김예슬, Identification of cromolyn sodium as an anti-fibrotic agent targeting both hepatocytes and hepatic stellate cells , PHARMACOLOGICAL RESEARCH , Vol.102 , pp.176 -183 (Dec, 2015) [논문] 백광현, 임기환, 구본희, 김진옥, 박상규, 박장준, HAUSP-nucleolin interaction is regulated by p53-Mdm2 complex in response to DNA damage response , SCIENTIFIC REPORTS , Vol.5 , No.12793 , pp.12793(1) -12793(12) (Aug, 2015) [논문] 박상규, 조진구, 이상원, 임대석, 김철훈, 홍신희, 윤강준, The antibody atliximab attenuates collagen-induced arthritis by neutralizing AIMP1, an inflammatory cytokine that enhances osteoclastogenesis , BIOMATERIALS , Vol.44 , pp.45 -54 (Mar, 2015) [논문] 박상규, 조진구, 양호빈, 조영준, 성종혁, 유민아, 김광일, Generation of Med28 Specific Monoclonal Antibodies , MONOCLONAL ANTIBODIES IN IMMUNODIAGNOSIS AND IMMUNOTHERAPY , Vol.34 , No.1 , pp.30 -35 (Feb, 2015) [논문] 박상규, 이준희, 홍신희, 이한나, 김철민, 권상모, 윤강준, 오배준, 김재현, 정석윤, Takayuki Asahara, 조진구, 김서윤, Tauroursodeoxycholic Acid, a Bile Acid, Promotes Blood Vessel Repair by Recruiting Vasculogenic Progenitor Cells , STEM CELLS , pp.1 -10 (Nov, 2014) [논문] 박상규, 이택기, 김왕균, 최준석, 송승용, 한준희, 성종혁, 김원석, 이현주, 조윤경, 황성주, 송순욱, 김지혜, Isolation of adipose-derived stem cells by using a subfractionation culturing method , EXPERT OPINION ON BIOLOGICAL THERAPY , Vol.14 , No.11 , pp.1551 -1560 (Nov, 2014) [논문] 박상규, 성종혁, 송순욱, 김지혜, 김왕균, Functional Regulation of Adipose-derived Stem Cells by PDGF-D , STEM CELLS , pp.1 -8 (Oct, 2014) [논문] 박상규, 윤태종, 권용수, 조희상, 허선희, 박경순, 이수홍, 황승일, 김영일, 제환준, 안국준, 조영석, 이학호, 이학종, 윤영일, Ultrasound-mediated gene and drug delivery using a microbubble-liposome particle system , THERANOSTICS , Vol.4 , No.11 , pp.1133 -1144 (Sep, 2014) [논문] 박상규, 정지혜, 박미리, 박미선, 임은진, Haengseok Song, 최은, 홍권호, 이동률, 고정재, 최영석, 김혜련, The expression of aminoacyl-tRNA-synthetase-interacting multifunctional protein-1 (Aimp1) is regulated by estrogen in the mouse uterus , MOLECULAR AND CELLULAR ENDOCRINOLOGY , Vol.5 , No.399 , pp.78 -86 (Aug, 2014) [논문] 박상규, Lina Jia, 이훈석, Chun Fu Wu, Juthika Kundu, 김용남, 신영기, Ozgur Cem Erkin, 최종선, 채승완, 양호빈, 최윤라, 왕리휘, SMAD4 suppresses AURKA-induced Metastatic Phenotypes via Degradation of AURKA in a TGF-beta-independent manner , MOLECULAR CANCER RESEARCH (Jul, 2014) [논문] 박상규, 김지혜, 김왕균, 성영관, 곽미희, 송승용, 성종혁, 이택기, 이현주, 김대덕, 서현민, 송순욱, 최준석, The molecular mechanism underlying the proliferating and preconditioning effect of vitamin C on adipose-derived stem cells , STEM CELLS AND DEVELOPMENT , Vol.23 , No.12 , pp.1364 -1376 (Jun, 2014) [논문] 박상규, 차병현, 김진수, 이수홍, 김희천, 김병수, 한동근, 안종찬, The role of tauroursodeoxycholic acid on adipogenesis of human adipose-derived stem cells by modulation of ER stress , BIOMATERIALS , Vol.35 , No.9 , pp.2851 -2858 (Mar, 2014) [논문] 박상규, 조진구, 김철민, 강아영, 박경수, 안병용, 정성수, 임기환, 백광현, 성종혁, 이경원, 김민, Herpesvirus-associated ubiquitin-specific protease (HAUSP) modulates peroxisome proliferator-activated receptor γ (PPARγ) stability through its deubiquitinating activity , JOURNAL OF BIOLOGICAL CHEMISTRY , Vol.288 , No.46 , pp.32886 -32896 (Nov, 2013) [논문] 박상규, 손우성, 이수홍, 김철민, 차병현, 윤강준, 김서윤, 박민철, ARS-interacting multi-functional protein 1 induces proliferation of human bone marrow-derived mesenchymal stem cells by accumulation of β-catenin via fibroblast growth factor receptor 2-mediated activation of Akt , STEM CELLS AND DEVELOPMENT , Vol.22 , No.19 , pp.2630 -2640 (Oct, 2013) [논문] 박상규, 성종혁, 김진경, 김지혜, 송승용, Reactive oxygen species-responsive miR-210 regulates proliferation and migration of adipose-derived stem cells via PTPN2 , CELL DEATH & DISEASE , Vol.4 (Apr, 2013) [논문] 박상규, 김규엽, 조영준, 강태희, Convergent evolution of two different random RNAs for specific interaction with methionyl-tRNA synthetase , BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , Vol.432 , No.2 , pp.281 -286 (Mar, 2013) 국제학술발표 [학술회의] 박상규, 김진옥, Development of Antibody Drug Conjugate Targeting c-Kit and Validation of Effectiveness in Cancer , 2020 생화학분자생물학회 International eConference (Sep, 2020) [학술회의] 박상규, 김광혁, 김진옥, Development of Full Human Antibody Targeting c-Kit and its Application to Treat cancer , American Association for Cancer Research (AACR) Virtual Annual Meeting (Jun, 2020) [학술회의] 박상규, 김광혁, 김진옥, Development of Full Human Antibody Targeting c-Kit and its Application to Treat Cancer , 생화학분자생물학회 동계학술대회 (Jan, 2020) [학술회의] 박상규, 김광혁, 김석호, 김진옥, Identification and Characterization of a Novel Peroxisome Proliferator-Activated Receptor α/γ agonist for the Treatment of Metabolic Disease , 2018 추계 약학회 국제학술대회 (Oct, 2018) [학술회의] 박상규, Development of therapeutic antibody for Rheumatoid arthritis , 2018 춘계 국제 약학회 (Apr, 2018) [학술회의] 박상규, 조진구, 엄윤정, 임기환, Shortening the cell cycle by MED28, mediator complex subunit, modulates aneuploidy in the breast adenocarcinoma , 한국 생화학분자생물학회 제8회 동계학술대회 (Jan, 2017) [학술회의] 박상규, 홍신희, Identification of Novel therapeutic target for arthritis treatment , 2016 International Conference of The Korean Society of Pharmaceutical Sciences and Technology (2016 한국약제학회 국제학술대회) (Dec, 2016) [학술회의] 박상규, 홍신희, Tauroursodeoxycholic Acid increases Viability of CD34+-derived Red Blood Cells , 대한약학회 70주년 국제학술대회 (Oct, 2016) [학술회의] 박상규, 조진구, ZNF224 promotes tumor growth : Identification of Novel Pathway , 대한약학회 70주년 국제학술대회 (Oct, 2016) [학술회의] 박상규, Antibody Therapeutics targeting Rheumatoid Arthritis , 2015 2nd International Symposium (Developing trends of a medicine for rare or obstinate disease and globalization) (Nov, 2015) [학술회의] 박상규, 조진구, 홍신희, Effect of ARS-interacting multi-functional protein 1 (AIMP1) antibody on collagen-induced arthritis , Frontiers in Stem Cells & Cancer (Mar, 2015) [학술회의] 박상규, 조진구, Tauroursodeocycholic acid, bile acid, induces blood vessel repair via stem cell mobilization , Frontiers in Stem Cells & Cancer (Mar, 2015) [학술회의] 박상규, 조진구, ZNF224 decreases p53 and p21 via MIR663A , Frontiers in Stem Cells & Cancer (Mar, 2015) [학술회의] 박상규, 유민아, Development and characterizaiton of human Med28 Specific Monoclonal Antibodies , Frontiers in Stem Cells & Cancer (Mar, 2015) 국내학술발표 [학술회의] 박상규, Development of Serum free chemically defined media for stem cell therapeutics , 2018 생명약학연구회-한국약제학회 동계 심포지움 (Feb, 2018) [학술회의] 박상규, 임기환, 조진구, MED28 increases the colony-forming ability of breast cancer cells by stabilizing the ZNF224 protein upon DNA damage , 통합생물학회 (Dec, 2017) [학술회의] 박상규, 홍신희, 엄윤정, 임기환, Characterizing and Generating of Monoclonal Antibody for Targeting α isoform Nectin-2 , 한국 생화학분자생물학회 제 8회 동계학술대회 (Jan, 2017) [학술회의] 박상규, First-in-class antibody development for rheumatoid arthritis , 제3회 아주대학교 의약학 공동심포지엄 (Nov, 2016) [학술회의] 박상규, AIMP1, a Novel Target for Arthritis , 2016년 생명약학 연구회 하계 심포지엄 (Jul, 2016) [학술회의] 박상규, Application of AIMP1 for Chondrogenic Differentiation , 약품생화학분자생물학분과 하계심포지엄 (Jun, 2016) [학술회의] 박상규, 중간엽 줄기세포의 효율적 배양기술 , 한국조직공학재생의학회 교육심포지엄 (Nov, 2015) [학술회의] 박상규, AIMP1을 타겟으로하는 류마티스성 관절염 치료용 항체 개발 , 치료용 단백질 개발 심포지움 (Jan, 2015) [학술회의] 박상규, 홍신희, 권상모, 조진구, Tauroursodeocycholic acid, bile acid, induces blood vessel repair , 한국 생화학 분자생물학회 동계 학술대회 (Jan, 2015) [학술회의] 박상규, 조진구, 유민아, Development of Med28 Specific Monoclonal Antibodies , 한국 생화학 분자생물학회 동계 학술대회 (Jan, 2015) [학술회의] 박상규, 조진구, 홍신희, The AIMP1 neutralizing antibody attenuates collagen-induced arthritis , 한국 생화학 분자생물학회 동계 학술대회 (Jan, 2015) 저서 및 번역 [저서] 박상규, 약품생화학 분자생물학 총정리 , pp.139~154 (Oct, 2015)
특허 및 기타	[특허] 박상규, 이상원, AIMP1을 포함하는 전신 홍반성 루프스 진단용 바이오마커 조성물 및 이를 이용한 전신 홍반성 루프스 진단 방법 (등록) (6835983) (R0420JP) (Feb, 2021) [특허] 박상규, 김진옥, 김광혁, c-kit에 대한 항체 및 이의 용도 (출원) (10-2019-0152304) (Nov, 2019) [특허] 박상규, 이상원, AIMP1을 포함하는 전신 홍반성 루프스 진단용 바이오마커 조성물 및 이를 이용한 전신 홍반성 루프스 진단 방법 (출원) (16/608,931) (R0420US) (Oct, 2019) [특허] 박상규, 손미권, 홍순선, 간질환 예방 또는 치료용 펩타이드 발명의 명칭 및 이를 유효성분으로 포함하는 조성물 (등록) (10-1996490) (Jun, 2019) [특허] 박상규, 이상원, AIMP1을 포함하는 전신 홍반성 루프스 진단용 바이오마커 조성물 및 이를 이용한 전신 홍반성 루프스 진단 방법 (출원) (10-2019-0032884) (Mar, 2019) [특허] 박상규, 유방암 예후 예측용 바이오마커 (등록) (10-1943157) (Jan, 2019) [특허] 박상규, PPARα/γ 이중 작용 활성을 갖는 신규 화합물 및 이를 유효성분으로 함유하는 대사질환 예방 또는 치료용 조성물 (등록) (10-1934197) (Dec, 2018) [특허] 박상규, 김진옥, c-kit 항체 개발 (출원) (10-2018-0120233) (Oct, 2018) [특허] 박상규, PPARα/γ 이중 작용 활성을 갖는 신규 화합물 및 이를 유효성분으로 함유하는 대사질환 예방 또는 치료용 조성물 (출원) (PCT/KR2018/006649) (Jun, 2018) [특허] 박상규, 이상원, AIMP1을 포함하는 전신 홍반성 루프스 진단용 바이오마커 조성물 및 이를 이용한 전신 홍반성 루프스 진단 방법 (출원) (PCT/KR2018/005001) (Apr, 2018) [특허] 박상규, 홍신희, 조진구, ＴＵＤＣＡ를 이용한 줄기세포 생물작용 활성 증가, 및 이를 포함하는 줄기세포 치료 보조제 (등록) (9,896,662) (R0420US) (Feb, 2018) [특허] 박상규, SCF를 중화하는 단일클론 항체 (출원) (10-2017-0143816) (Oct, 2017) [특허] 박상규, 이상원, AIMP1을 포함하는 전신 홍반성 루프스 진단용 바이오마커 조성물 및 이를 이용한 전신 홍반성 루프스 진단 방법 (출원) (10-2017-0055247) (Apr, 2017)

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